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15 January 2014
Time: 16:00 to 17:00
Location: Seminar Room 1.53g

Oscillating microbubbles and nanoparticle self-assembly/disassembly



Valeria Garbin, Imperial College London

The dynamics of complex fluid interfaces strongly affects transport phenomena in systems that are central to industrial and biomedical flows: surfactant self-assembly promotes emulsification, nanoparticles at fluid interfaces catalyze biphasic reactions, and controlled poration of biomembranes can aid drug delivery. In this talk I will discuss two systems in which unexpected effects arise due to the dynamics of complex interfaces.

 

 

First, I will present a study on the dynamics of phospholipid-coated microbubbles, which are used as carriers for ultrasound-assisted drug delivery. Precision measurements of the forces acting on microbubbles in ultrasound enabled us to quantify the strength of ligand-receptor mediated adhesion at extreme loading rates of 1 N/s, several orders of magnitude larger than is accessible to AFM.

 

 

The second part of the talk focuses on the dynamics of interfacial nanoparticle monolayers. In experiments on self-assembly of nanoparticle monolayers on drops (Pickering emulsions), we observed mechanically forced desorption of nanoparticles from the oil-water interface. Our finding points to new opportunities for engineering the dynamic response of nanoparticle monolayers by tuning nanoparticle interactions, with applications in green chemistry and functional nanomaterials.