School of Chemistry

Andrew Wilson

ERC Fellow/Reader
Research section: Organic Chemistry

Contact details

Keywords

Synthetic chemistry
Molecular recognition and self-assembly
Chemical Biology
Supramolecular Materials

Research interests

Our group is interested in using synthetic molecules to solve problems in Chemical Biology and Materials Science. The major theme of our multidisciplinary program involves the development and application of robust methods for synthesis of designed compounds. These compounds are used as tools to study molecular recognition and self-assembly using modern characterisation techniques. Current areas of interest include: the development of inhibitors of protein-protein interactions - a novel target class for pharmaceutical intervention, structural and mechanistic studies of amyloid assembly and development of supramolecular polymers based on novel hydrogen-bonding motifs.

Useful links

Wilson Group Pages   
   
   

Selected publications

A. Gooch, A. M. McGhee, M. L. Pellizzaro, C. I. Lindsay, A. J. Wilson*: ‘Substituent Control over Dimerization Affinity of Triply Hydrogen-Bonded Heterodimers’, Org. Lett. 2011,13, 240-243.

M. H. Filby, J. Muldoon, S. Dabb, N. C. Fletcher, A. E. Ashcroft and A. J. Wilson*: ‘Protein surface recognition using geometrically pure Ru(II) tris(bipyridine) derivatives’, Chem. Commun., 2011, 559-561.

F. Campbell, J. P. Plante, T. A. Edwards, S. L. Warriner, A. J. Wilson*: ‘N-Alkylated Oligoamide alpha-Helical Proteomimetics’, Org. Biomol. Chem. 2010, 8, 2344-2351.

A. J. Wilson*: ‘Inhibition of Protein-Protein Interactions Using Designed Molecules’, Chem. Soc. Rev., 2009, 38, 3289-3300.